【药品名称】 苦参素注射液 ( Marine Injection)
【成    份】 本品主要成份为苦参素。辅料：无。
【性    状】 本品为几乎无色或微黄色的澄明液体。
【适 应 症】 用于慢性乙型病毒性肝炎及肿瘤放疗、化疗引起的白细胞低下和其他原因引起的白细胞减少症。
【规    格】 2ml:0.2g×6支/盒
【用法用量】 肌肉注射。用于慢性乙肝，每次0.4～0.6g（2-3支），每日1次；用于升高白细胞，每次0.2g（1支），每日2次。静脉滴注。用于慢性乙肝，每日1次，每次0.6g（3支），可溶于5%葡萄糖注射液或0.9%的氯化钠注射液100～250ml中静脉滴注，滴注速度以每分钟60滴为宜。二月为一个疗程，或遵医嘱。
【注意事项】
1、请在医生指导下使用本品。
2、严重肾功能不全者，不建议使用本品。
3、长期使用应密切注意肝功能变化，肝功能衰竭者禁用。
【孕妇及哺乳期妇女用药】  孕妇不宜使用。哺乳期妇女慎用。
【儿童用药】  尚无儿童用药经验。
【老年患者用药】 减量或遵医嘱。
【药物相互作用】 尚不明确。
【贮　  藏】 遮光，密闭，在阴凉处保存。
【有 效 期】 24个月
【批准文号】 国药准字H20057511
【生产企业】
企业名称：吉林省通化振国药业有限公司
生产地址：吉林省通化县湾湾川植物园
邮政编码：134100
功效与特点：
苦参碱类作用特点是：
1.杀伤肿瘤细胞  抑制肿瘤细胞增殖和诱导肿瘤细胞的凋亡。
2.防止肿瘤的转移与复发  苦参碱可能通过减低癌细胞的粘附性和管道内皮细胞的通透性来减少肿瘤的转移。抑制肿瘤新生血管的形成。
3.预防肿瘤病人发生恶液质，改善肿瘤病人生存质量  大量研究显示晚期肿瘤患者在进行放化疗治疗的同时，使用苦参碱氯化钠注射液可明星地降低由放化疗导致的毒副作用，明显改善肿瘤病人的生存质量。
4、苦参素具有抗炎、抗病毒、保肝降酶、抗肝纤维化作用。
Marine  Injection
【Name of Drug】 Marine  Injection
【Ingredients】 Main ingredient of this product is Marine. Excipients: none
【Characteristics】 This product is almost colorless or slight yellow clear liquid.
【Indications】 It is applied to the treatment of chronic viral hepatitis B and leukocyte decrease induced by radiochemotherapy and leucopenia induced by other reasons.
【Specification】2ml:0.2g(Marine) ×6pcs/box
【Usage and Dosage】Intramuscular injection: for chronic hepatitis B, 0.4-0.6g (2-3pcs) each time, once a day; increasing leukocytes: 0.2g (1 pcs) each time, twice a day. Intravenous injection: for chronic hepatitis B, once a day, 0.6g (3 pcs) each time, soluble in 5% glucose injection or 0.9% NaCl injection 100-250ml, 60 drops/min. Two-month treatment makes a session or in accordance with medical advice.
【Precautions】
1. Use the product with the guide of doctor
2. The product is not recommended for those with severe renal dysfunction.
3. For long-term use, it is required to notice closely the changes in liver function. The product is prohibited for liver failure.
【Medication for Women in Pregnancy and Lactation】  The product is not suitable for pregnant women and is used cautiously for women in lactation.
【Medication for Children】  Experience is unknown in medication for children.
【Medication for Ages】 Reduce dose or obey medical advice.
【Interaction of Drugs】 Unknown
【Storage】 Avoiding light, sealing, storing in cool place
【Validity】    24 months
【Approval Number】 National Pharmaceutical Approval Number H20057511
【Manufacturing Enterprise】  Jilin Tonghua Zhenguo Pharmaceutical Limited Company
【Address】   Botanic Garden, Wanwanchuan, Tonghua County, Jilin Province
Characteristics of matrines:
1. Kill tumor cell, inhibit proliferation of tumor cell and induce apoptosis of tumor cell.
2. Prevent from metastasis and recurrence of tumor. Matrine reduces tumor metastasis and suppresses new vasculization of tumor probably through decreasing adhesion of tumor cell and permeability of tubal endothelial cell.
3. Prevent from cachexia in tumor patient and improve survival quality of patient. A large amount studies has been indicated that during radiochemotherapy for late stage of tumor, Matrine and Sodium Chloride Injection can reduce toxic side effects induced by radiochemotherapy apparently and improve survival quality of tumor patient.
4. Oxymatrine acts on anti-inflammation, anti-virus, protecting the liver, reducing aminotransferase and anti-hepatic fibrosis.